Researchers bolster antitumor immune defenses using cancer vaccines made from DNA origami. “One of the attractive things about DNA origami is how relatively simple it is for anybody to design,” Shih ...

DNA, the medium of life, is so deeply associated with the biochemical world that considering its nonbiological applications may seem far-fetched. However, for researchers in the 1980s and 1990s ...

A coarse-grained model of the DNA origami lilypad used in the study. The tails hanging down indicate where redox reporters are located. For scale, the diameter of the disk is approximately 80 nm.

Similarly to the artistic technique of folding paper into ornate shapes, DNA origami is a self-assembling technique of precisely folding single-stranded DNA scaffolds into well-defined nanostructures.

Inspired by biological systems, materials scientists have long sought to harness self-assembly to build nanomaterials. The challenge: the process seemed random and notoriously difficult to predict.

The sensor uses a DNA origami scaffold, which consists of two arms connected by a molecular “hinge.” Each arm is tagged with a fluorescent dye, and the distance between the tags is recorded by means ...

mRNA vaccines saved millions of lives during COVID-19 but have limitations like waning immunity and complex production. Scientists are now testing a new platform called DoriVac, which uses folded DNA ...

Florian Praetorius and Prof. Hendrik Dietz of the Technical University of Munich (TUM) have developed a new method that can be used to construct custom hybrid structures using DNA and proteins. The ...

To assemble these minuscule structures, researchers first create a scaffold: a long piece of single-stranded DNA with a carefully designed sequence of bases. Then they add hundreds of shorter DNA ...

An international research team led by scientists from Skoltech has developed a method to position molecules on the surface of ultrathin materials with unprecedented precision using molecular DNA ...